Posts Tagged ‘kidney transplant’

In the News: Emory Transplant Center Kidney Living Donor Program

organ-donor260x200Emory Transplant Center has recently made headlines with their Kidney Living Donor Program. Stories featured on FOX NEWS Health and in Atlanta magazine highlight individuals who have given the gift of life through organ donation. One story features Beth Gavin, a medical reporter for FOX5, who altruistically donated her kidney to a stranger that kicked off a string of six transplants. The other highlights an Atlanta police officer who donated a kidney to a stranger to allow his wife to be able to receive a kidney from someone else through paired donor exchange.

A kidney paired donor exchange occurs when a person in need of a kidney transplant has an eligible living donor, but the living donor is unable to give to their intended recipient because they are incompatible. Therefore, an exchange with another donor/recipient pair is made. This kidney paired donation enables two incompatible recipients to receive healthy, more compatible kidneys.

“Emory began its Kidney Paired Donor Exchange Program in 2010, and we have been participating in the National Kidney Registry since 2012,” says Nicole Turgeon, MD, associate professor of surgery, Emory University School of Medicine and surgical director of the Paired Donor Exchange Program. “Paired donor exchange gives patients an opportunity to receive a living donor kidney transplant from a loved one or friend, despite incompatible blood types and positive crossmatches. In paired donation, a donor and recipient are matched with another incompatible donor and recipient pair, and the kidneys are exchanged between the pairs.”

According to Dr. Turgeon, there are currently more than 100,000 people on the kidney transplant waiting list. The discrepancy between the number of organs available and the number of people on the waiting list continues to grow. The Emory Transplant Center is the state’s largest transplant center performing the highest volume of kidney transplants in Georgia.

FOX NEWS Health Story 

Atlanta Magazine Story

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Your Organ Donation Questions Answered: Takeaways from Our Live Chat

organ-donor260x200Thank you to everyone who joined us for Emory Transplant Center’s live web chat on the topic of organ donation. With April serving as Donate Life month, we wanted to raise awareness around organ donation and answer your specific questions. Lead Transplant Coordinator, Sharon Mathews, MS, RN, CPTC, answered questions about organ donation, including how many people are currently waiting for an organ, what organs can be donated, and who can donate. She also discussed Emory Transplant Center’s living donor and paired donor exchange programs.

Below are just a few highlights from the chat. If you missed this informative chat, check out the full list of questions and answers located on our chat transcript. You may also visit the Emory Transplant Center website for more information. And for more information on how to become an organ donor, visit donatelife.net.

Question: How long can an organ stay viable during transport?

Sharon Mathews: For solid organs, heart and lungs are viable for 4-6 hours, livers up to 12 hours, the pancreas is viable for 12-18 hours and kidneys remain viable up to 24- 30 hours on ice. The goal is to transplant the organs within 8 hours or less of being recovered.

Question: Do you have to be on kidney dialysis before you can be put on the wait list for a kidney?

Sharon Mathews: No, if you have been referred to a transplant center and are undergoing evaluation for transplant, you can have potential living donors call in on your behalf. The initial screening tests can be done at this point in the process. However, you will not become active on the UNOS wait list until your kidney function meets protocol for transplantation.

Question: If my blood type doesn’t match my recipient’s what are my options?

Sharon Mathews: At Emory we are involved with the National Kidney Registry (a paired donor exchange program). In a paired exchange, a donor will donate their kidney to another recipient in exchange for a compatible kidney for their loved one. This can occur on the same day. So while they didn’t walk away with your kidney, they received a kidney that was the best match donor possible.

Currently more than 115,000 men, women and children are awaiting a life-saving transplant. They are in need of organs, tissue, and bone marrow which can all be transplanted if donors were available, giving recipients a second chance at life. Perhaps the most important message from the live chat is the one on the importance of organ donation and how it can have a huge impact on people’s lives.

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Giving the Gift of Life: Former Marine Donates Kidney to National Guardsman

MarineGuardsmanPhotoThe Emory Transplant Center loves to share heartwarming stories that happen right here in our Center. As we celebrate Donate Life month, we would like to honor those who have graciously made the decision to give the gift life. Former Marine, Temple Jeffords, is one of those individuals. He made the decision to donate one of his kidneys to help out a fellow serviceman.

It all started with a plea for help via social media. Suffering with Stage 4 kidney disease, 28-year-old Dustin Brown, Army National Guardsman, relied on dialysis machines to rid his body of waste, salt and water that his failing kidneys could no longer do. Doctors told him a kidney transplant was needed.

Dustin connected with Kristi and Raleigh Callaway. Raleigh Callaway, a Greensboro, Georgia, police officer, received a new kidney in 2014 following a Facebook post publicly appealing for help.

Soon Brown, posing with his wife and five-year-old son, had a similar Facebook post on the Callaway’s page, desperately searching for a new kidney.

Former Marine, Temple Jeffords, saw the plea for help and contacted Kristi Callaway and the Emory Kidney Transplant Program. A few weeks later, 44-year-old Jeffords learned he was a match for Brown.

“I have never thought about donating a kidney to anyone, but when I saw another serviceman’s need for help, I wanted to help,” says Jeffords. “The testing and donating processes are simple.”

Living donor kidney transplants, such as this one, make the wait times shorter for critically-ill patients, while also providing the greatest chances for long-term success,” says Nicole Turgeon, MD, surgical director of the Paired Donor Kidney Exchange Program at Emory Transplant Center.

“I am so thankful for Temple,” said Brown, just days after his kidney transplant surgery. “Brothers in arms are always brothers, no matter what. He is a super hero in our family.”

Watch the story featured on ABC News here.

Watch the story featured on Fox News here.

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about kidney transplant and the Emory Living Donor Kidney Program 

Emory Transplant Center Receives Special Visit from Former NFL Player and Kidney Transplant Recipient

transplantThe Emory Transplant Center received a special visit from former NFL player Donald Jones, who received his own kidney transplant in 2013 following kidney disease. On Wednesday, March 16th, Jones visited with faculty and staff at Emory Transplant Canter and then went on to meet with kidney transplant patients at Emory University Hospital. It was quite a delight for our patients.

Jones was a wide receiver for the Buffalo Bills from 2010 to 2012. While playing with the Bills, he began developing high blood pressure and experienced some vision loss. Then the New England Patriots signed him in 2013. But only a few months later, he was diagnosed with IgA nephropathy, a kidney disorder that occurs when IgA, a protein that helps the body fight infections, settles in the kidneys. Treatment for the disorder is dialysis or a kidney transplant.

Jones retired from the NFL in August 2013 at just 25 years old. In December 2013, Jones received a life-saving kidney transplant from his father. Since then, he has been traveling the country raising awareness and fundraising for kidney disease and IgA nephropathy.

Emory Transplant Center faculty and staff had the opportunity to attend a book signing of Jones’ recently published autobiography, The Next Quarter: Scoring Against Kidney Disease. And Emory kidney transplant recipients Robert Burns and Angela Parks, both from Decatur, were delighted to have Jones drop by their Emory University Hospital rooms.

While at Emory, Jones was also interviewed for an educational video about dialysis and kidney transplantation. Rachel Patzer, PhD, MPH, assistant professor of surgery in Emory University School of Medicine and Rollins School of Public Health, recently received funding to develop a video following her research study about kidney transplant rates, published in the Journal of the American Medical Association in August 2015.

The study found only about one in four patients with end-stage renal disease in Georgia was referred by a dialysis facility to a transplant center for evaluation within one year of starting dialysis. Patzer hopes the video will educate dialysis patients about transplant as a treatment option and encourage patients to discuss transplant with their providers and family members.

The video, once released, will be distributed to dialysis centers throughout the U.S. that have low rates of transplant or racial disparities in access to transplant.

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about kidney transplant and the Emory Kidney Transplant Program

Giving the Gift of Live: Understanding Organ Donation Live Chat- April 12, 2016

organ-donor260x200April serves as National Donate Life month – raising awareness around organ donation and celebrating those who have given the precious gift of life to another. Currently more than 115,000 men, women and children are awaiting a life saving transplant. They are in need of organs, tissue, and bone marrow which can all be transplanted if donors were available, giving recipients a second chance at life. Understandably, potential donors may have reservations about organ donation.

To get the facts and learn more about organ donation, join Sharon Mathews, MS, RN, CPTC, of the Emory Transplant Center for a live chat on Tuesday, April 12th from Noon – 1PM. She will answer all of your questions about organ donation, including how many people are currently waiting for an organ, what organs can be donated, and who can donate. She will also discuss Emory Transplant Center’s living donor and paired donor exchange programs.

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Belatacept Provides Better Kidney Survival Rates than Current Standard of Care

transplant drugA study of kidney transplant recipients has shown for the first time that the drug belatacept (Nulojix), which controls the immune system and prevents graft rejection, has a better record of patient and organ survival than a calcineurin inhibitor, the current standard of care.

Patients who have undergone kidney transplant are required to take medications to prevent their immune systems from rejecting their new organs. A calcineurin inhibitor (CNIs) is generally used for post kidney transplant patients, but long-term use can damage transplanted kidneys and may lead to cardiovascular disease and diabetes.

Belatacept acts as a “co-stimulation blocker,” inhibiting one of two signals the T cells need to trigger an immune response. And unlike the currently used CNIs, it is not toxic to the kidney. In fact, it helps preserve the function of the kidney over the long term and is more effective in suppressing antibodies against the kidney, which are important causes of organ loss.

Emory University School of Medicine Dean and kidney and pancreas transplant surgeon, Dr. Christian Larsen, played a key role in developing belatacept, together with Emory Transplant Center Executive Director and Livingston Professor of Surgery, Dr. Thomas Pearson. Belatacept was approved by the FDA in 2011 and is produced by Bristol Myers Squibb.

The study, called BENEFIT (Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression Trial), was sponsored by Bristol-Myers Squibb and began in 2006. FDA approval of belatacept in 2011 was partly based on the first three years of results. Results from the worldwide study, led by Dr. Larsen and University of California San Francisco kidney transplant surgeon, Dr. Flavio Vincenti, were published in the Jan. 28 issue of the New England Journal of Medicine.

The seven-year, multi-center study showed that kidney transplant recipients taking belatacept experienced a rate of mortality and graft loss significantly lower than patients taking a CNI-based regimen. The risk of death or loss of the transplanted kidney after seven years was 12.7 percent for belatacept, compared to 21.7 percent for cyclosporine A.
“While the best uses of belatacept still need additional definition, these results indicate that using belatacept as standard of care has the potential to improve long-term outcomes that matter to patients,” says Dr. Larsen.

Belatacept is given by infusion monthly at a doctor’s office, in contrast to CNIs, which are taken in daily pills at home. Many U.S. insurance companies now cover belatacept as medically necessary for kidney transplant patients.

Fox 5 Atlanta Health Reporter Gives the Gift of Life

fox5 atlantaFox 5 Atlanta’s health reporter, Beth Galvin, started a chain of her own this past June when she donated her kidney at Emory Transplant Center for kidney transplant. In her two decades as a TV reporter, she saw many patients with end-stage renal disease on dialysis, and she wanted to help. She also was inspired by a story she covered in 2013 on Fox 5 about Chamblee Assistant Police Chief Mike Beller, a father of five who donated his kidney at Emory University Hospital (EUH). Galvin took a few weeks off from work and donated her own kidney at EUH last summer. Dr. Nicole Turgeon, Surgical Director of the Paired Donor Exchange Program, was her surgeon.

Galvin told her story at the October 24th Atlanta Trends in Transplant conference, hosted by Georgia Transplant Foundation. “I never expected the donor journey to be so emotional and spiritual,” she wrote on her Facebook page before her speaking engagement. “I began the process because I felt my inner compass was pointing me in this direction. Then, I stuck with it because I kept seeing signs I was on the right path.”

Galvin’s donated kidney was flown to the University of California at Los Angeles, where it transformed the life of a 41-year-old man on the waitlist there. He is a married father of two children and a volunteer baseball and softball coach. This was his second kidney transplant, which has saved him from the rigors of 4 a.m. dialysis before going to work. Galvin was one of six donors in a chain facilitated by the National Kidney Registry that ended up with six recipients who received new kidneys across the country.

Read Galvin’s first-person account in the fall issue of Emory Medicine magazine. To watch her story on Fox 5, click here.

Learn more about the Emory Transplant Center’s living donor program.

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Emory Transplant Center Ranks 7th Nationally

The Emory Transplant Center ranks 7th among transplant programs across the nation based on adult transplant volumes. In calendar year 2014, we performed 441 adult transplants that placed us 7th overall, tied with Barnes-Jewish Hospital. Our top 10 ranking puts us among good company.

 

 

 

 

 

And with the recent release of the latest Scientific Registry of Transplant Recipients (SRTR) data, it revealed that all Emory solid organ programs, when risk-adjusted, are similar to if not statistically different from the national data and meet expectations for performance set by the United Network for Organ Sharing (UNOS) Membership Professional Standards Committee (MPSC).

The new SRTR center-specific data included the following one-year graft and patient survival rates for our patients:

Heart:
Patient survival rate: 90.4% (actual) vs. 90.75% (expected)
Graft survival rate: 80.95% (actual) vs. 84.3% (expected)

Kidney:
Patient survival: 98.1% (actual) vs. 97.4% (expected)
Graft survival: 95% (actual) vs. 94.4% (expected)

Kidney/Pancreas:
Patient survival: 100% (actual) vs. 97.9% (expected)
Graft survival: 100% (actual) vs. 95.8% (expected)

Liver:
Patient survival: 93.8% (actual) vs. 91.6% (expected)
Graft survival: 91.7% (actual) vs. 89.2% (expected)

Lung:
Patient survival: 84.7% (actual) vs. 87.1% (expected)
Graft survival: 84.5% (actual) vs. 90% (expected)

*adults; cohort 1/1/12 – 6/30/14 (deaths and re-transplants were counted as graft failures)

Also of note, the Emory Kidney Transplant program’s three-year graft survival remains statistically greater than expected (p < 0.05) with outcomes of 89.48% (actual) vs. 86.29% (expected).

Our experience coupled with continued excellent outcomes in all solid organ programs make the Emory Transplant Center a leading transplant destination in the Southeast and the nation, serving patients in Georgia and bordering states. We are proud to be your transplant center.

Improving Dialysis Patients’ Lives Through Kidney Transplantation

Emory Transplant Center continues to be a leader in research by studying ways we can better bring the benefits of kidney transplantation to Georgia residents. Several Emory studies have documented that receiving a kidney transplant before dialysis, or soon after beginning treatment, can improve patient outcomes and quality of life.

A recent study conducted by the Emory Transplant Center, along with two other healthcare systems in Georgia and the Southeastern Kidney Transplant Coalition, looked at why patient referral rates from dialysis centers to transplant facilities were so low. They found that three-quarters of Georgia patients on dialysis were not even being evaluated for a possible kidney transplant within their first year of dialysis.

“The study found that fewer than 28% of Georgia dialysis patients were referred to one of the state’s three adult kidney transplant centers within a year of starting dialysis,” reports Dr. Stephen Pastan, Medical Director, Emory Kidney Transplant Program, reports.

Georgia has the lowest kidney transplant rate in the country. U.S. regulations require that all dialysis centers in Georgia inform patients of kidney transplantation as a treatment option within 60 days of starting dialysis. Yet the study identified 15 Georgia dialysis facilities that referred zero patients within one year of dialysis start. The dialysis facilities with the lowest transplant referral rates were more likely to be non-profit, have more patients, and a higher patient-to-social worker ratio. Kidney transplantation is a typically less expensive intervention than ongoing dialysis and one that also promises greater longevity and a better quality of life.

One of the first key steps for many patients to receive kidney transplantation is to hear about its life-changing benefits at a dialysis center. This study illustrates the need for further measures to improve overall referral of patients to kidney transplantation.

Learn more about the Emory Kidney Transplant Program or call us at 1-855-EMORYTX (366-7989)

iCHOOSE Kidney – An Education App for Prospective Kidney Transplant Patients

iChoose Kidney AppFor patients suffering from end-stage renal disease (ESRD), there are two major treatment options: dialysis and kidney transplant. Of these two options, medical studies have shown that receiving a kidney transplant offers a better chance of survival and quality of life, eliminating the need for hours of dialysis treatment.

Although it is required by law for clinicians or physicians to discuss kidney transplant as a treatment option for their ESRD patients, Emory epidemiologist Rachel Patzer, PhD, MPH, assistant professor of surgery, says that many eligible patients are not being referred for kidney transplantation. Through her research, Patzer found that such disparities were often present in regions outside the Atlanta area.

“There are disparities in who is getting access to that information about transplant, which I think is leading to some of the disparities we see in access to getting on the waiting list and receiving a transplant,” Patzer says.

In order to address these treatment disparities and help patients understand the best treatment option for their individual cases, Patzer and the Emory transplant team created the iCHOOSE Kidney iPad application. The iCHOOSE Kidney app is a shared-decision making tool for providers or clinicians to use with their patients to inform them about potential risks and benefits of each treatment. “The app basically walks you through different risks for treatment options,” Patzer says.

While Patzer says the optimal treatment for kidney disease is transplant, she says this depends on patients’ individualized risk profile, which includes factors such as their age and other possible medical conditions they may have.

Upon a patient’s initial diagnosis of end-stage kidney disease, physicians or clinicians can enter in patient data into the iCHOOSE Kidney app, which in turn calculates the risks of dying on dialysis versus a kidney transplant. The app calculates both relative and absolute risks based on data from a national database of almost 700,000 patients.

The app tries to keep things simple for patients by presenting data in a picture format. Patzer says illustrating information visually is one of the best ways to convey risks to patients. “Showing patients you’re going to live this many years longer or that this is 10 times better is really more powerful than just giving them the average,” Patzer says.

The app is currently being used at the Emory Transplant Center and in the surrounding community. Patzer says that the Emory transplant surgeons and nephrologists use the iCHOOSE Kidney app as part of their communication and education with patients. You can find the iChoose Kidney app by searching your App Store.