News

Emory Transplant Center is a Top 10 Transplant Center in the U.S.

Living Organ Donation Donate Life MonthThe latest data from OPTN/UNOS of adult organ transplants performed in 2012 show that the Emory Transplant Center performed 426 transplants, making it the largest transplant center in the state and the 10th largest in the country. If we add the 60 pediatric transplants performed at Children’s Healthcare of Atlanta, the ETC is the 5th largest transplant center in the country.

Of course, the ETC is much more than these numbers, but volume is one indication of just how busy our center is — and our programs are growing. In 2011, Emory performed 360 adult and 70 pediatric transplants. That means the total number of transplants increased 13% from 2011 to 2012. Each program is growing, too. The kidney program expanded from 204 transplants in 2011 to 230 in 2012, and the liver program grew from 93 transplants in 2011 to 111 in 2012. There were 11 kidney and pancreas transplants at the ETC in 2011 and 17 in 2012. The heart team transplanted 23 in 2011 and 34 in 2012, and the lung program transplanted 29 in 2011 and 34 in 2012.

This accomplishment never would have been possible without the gracious gifts of life organ donors provide to our transplant recipients. We are ever grateful to the donors who have indicated their wishes and the families that have made the decision to donate and save or restore the lives of our patients.

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Emory Heart Transplant Patients Celebrate the Gift of Life!

Heart transplant gift of lifeOur Emory transplant surgeons help facilitate the tremendous gift of organ donation and renewed life by performing approximately 60-70% of all heart transplant procedures in Georgia each year. On an annual basis, approximately 50 new Georgia adults receive heart transplants each year, and recently, over 100 of our Emory Heart Transplant patients and their families gathered together to celebrate this gift of life.

Watch this heartwarming Fox 5 News piece and meet some of our patients whose lives have been changed thanks to their heart transplant procedures.

Emory Transplant Center Performs First Triple Organ Transplant Procedure in Georgia

The team at the Emory Transplant Center has performed more organ transplants in the state of Georgia than any other transplant center. Because the Georgia community trusts the expertise of our transplant team, we have performed some of the most complex transplant procedures in the area. Our team performed the first hand transplant in the state of Georgia and the Southeast, for example, and we’ve performed over half of the multi-organ transplants in Georgia. While you’ve seen us share stories like that of Jo Ellen Kimball and her double lung transplant, multi-organ transplants are rare, making up just over 1% of all transplant procedures conducted in Georgia since 1988. But even more rare, is a double transplant involving a heart and a liver, with only 60 of these procedures having been performed in the U.S. And even more rare, a triple transplant, involving the transplantation of a heart, liver and kidney.

Stephanie Lindstrom

Stephanie Lindstrom

Today, thanks to a triple organ transplant, a 37-year-old mother of two in Georgia is celebrating Christmas with a renewed spirit of hope and thankfulness this year. Just five months ago, Stephanie Lindstrom received a triple organ transplant at Emory University Hospital, the first triple transplant ever to be performed in the state of Georgia.

Following a lifetime battle of congenital heart complications, Stephanie’s condition became critical this summer when she was told she would need not only a new heart, but that she would also need a new liver and kidney. All other interventions to help her were not successful.

“Because of Stephanie’s heart failure, she developed liver failure. Then she became septic, which led to kidney failure. So a triple organ transplant was our only hope to save her,” says Stuart Knechtle, MD, professor of surgery at Emory University School of Medicine and director of the Adult Liver Transplantation Program.

Stephanie, a former marathon runner, was born without a tricuspid valve, which helps move blood through the heart in the right direction. She had four surgeries as a child to repair the problem. After she graduated from college, more heart valve problems occurred, but this time, with her mitral valve. Doctors diagnosed Stephanie with mitral valve regurgitation and said it needed to be corrected.

Stephanie, who lives in South Carolina, scheduled an appointment with Wendy Book, MD, associate professor of medicine at Emory and medical director of Emory’s Adult Congenital Heart Disease Program. “When I first met Stephanie, I immediately knew she was a resilient, strong willed person who was a fighter,” says Dr. Book. “We knew her heart and liver were in bad shape because of her congenital complications, but problems with her kidney had not yet surfaced.”

In September 2011, Stephanie was placed on the waiting list for a heart and a liver. In May 2012, she contracted cytomegalovirus, and was admitted to the hospital to be put on dialysis and breathing machines. At that point, she was moved up on the waiting list for her new organs, which now included a kidney.

On July 7, 2012, doctors got the call that a match had been found for Stephanie. On that day, both her heart and liver were transplanted during a lengthy surgery.

First Brian Kogon, MD, surgical director of the Adult Congenital Heart Disease Program transplanted her new heart, assisted by David Vega, MD, director of Emory’s Heart Transplant Program. Then Knechtle and transplant surgeon Andrew Adams, MD, transplanted the liver. The following day, Knechtle transplanted her kidney. All three organs came from the same donor.

“The risks for a triple organ transplant are very high for a patient with a three-system failure, and one we had never attempted before,” says Kogon. “Her previous surgeries and critically-ill state at the time of the transplants made things challenging. But Mrs. Lindstrom’s age and determination to survive made her an ideal candidate for these procedures.”

Stephanie spent the next three months at Emory University Hospital recovering, while battling complications. She was able to return home in October 2012, five months after she was admitted.

“I am so grateful to the doctors, nurses and support staff who made these transplants possible,” says Stephanie. “They have given me a new lease on life. The holiday season has truly taken on such a special meaning to my family and me this year because of the many gifts we have been given.”

Dr. Thomas Pearson Named New Emory Transplant Center Director

Dr. Thomas C. PearsonAs a follow-up to our recent post announcing Emory Transplant Center’s own Christian P. Larsen, MD, DPhil as the new dean of the Emory University School of Medicine, vice president for Health Center Integration for the Robert W. Woodruff Health Sciences Center, and chairman of the Board of Directors of The Emory Clinic, we wanted to follow-up with more exciting news. Thomas C. Pearson, MD, DPhil, has been named executive director of the Emory Transplant Center, effective January 15, 2013. Pearson currently is associate director of the Emory Transplant Center, a position he has held since the center’s founding in 2001. He is surgical director of the kidney and pancreas transplant program and Livingston Professor of Surgery in Emory University School of Medicine. He also is an affiliate scientist at Yerkes National Primate Research Center.

“I am so pleased to have Tom Pearson take the reins as the executive director of the Emory Transplant Center. Tom and I have been the closest of friends and collaborators for the past 25 years,” says Larsen. “No one has contributed more to the Emory Transplant Center and our patients than Tom. His impact spans the strategic direction of the center, the culture of collaborative multidisciplinary care and research and the countless hours he gives day and night to patient care. I cannot imagine a more qualified physician, researcher or terrific individual to lead the Transplant Center on its future course.”

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Dr. Christian Larsen Named New Dean of Emory University School of Medicine

Christian Larsen, Emory Transplant Center Director

Dr. Christian Larsen

An internationally recognized leader in transplant surgery and immunology, Christian P. Larsen, MD, DPhil, has been named dean of Emory University School of Medicine.

Larsen is currently chair of the Department of Surgery at Emory University School of Medicine, director of Surgical Services for Emory Healthcare and executive director of the Emory Transplant Center. He holds endowed positions as the Joseph Brown Whitehead Professor of Surgery and the Carlos and Marguerite Mason Professor in the Emory School of Medicine.

“Over 22 years as an Emory faculty member, Dr. Larsen has demonstrated his skills as an outstanding surgeon, scientist, teacher and colleague, and most important, as a respected leader with the integrity and vision to build innovative new models of integrated patient care. He has excelled at moving medicine and care delivery forward, not only at Emory, but on a national level, says S. Wright Caughman, MD, Emory executive vice president for health affairs and CEO of the Woodruff Health Sciences Center.

Dr. Larsen will assume his new role as dean effective January 15, 2013, at which time he will also serve as vice president for Health Center Integration for the Robert W. Woodruff Health Sciences Center and as chairman of the Board of Directors of The Emory Clinic. To learn more about Dr. Larsen and his appointment as dean of the Emory University School of Medicine, check out the story in the Emory news center.

Emory Receives $20 Million Grant from NIH for Continued Transplant Research

Emory Transplant CenterIn the last few years, thanks to the development of anti-rejection drug therapies, outstanding breakthroughs in short-term outcomes have been achieved among organ transplant patients. We first introduced you to belatacept on our blog in September of 2010, while the medication was being studied by our team of doctors and researchers. Then in June of last year, we announced the FDA’s approval of belatacept and its confirmed ability to provide a less toxic alternative to the standard anti-rejection medications, including calcineurin inhibitors like cyclosporine.

Even with these developments, though, significant challenges remain for patients over the long term with organ rejection and drug toxicity that often leads to cardiovascular disease, infection or cancer.
To help overcome these challenges, a new $20 million grant has been bestowed upon Emory from the National Institute of Health to allow physician/researchers to develop better treatments for organ transplant recipients that help avoid both organ rejection and drug toxicity. The new grant builds upon more than 18 years of groundbreaking research by Emory scientists—such as the investigation into belatacept—that has already significantly advanced the transplant field.

Christian Larsen, Emory Transplant Center Director

Dr. Larsen

“Despite tremendous advances in immune drug therapy, the fact remains that organ recipients still must take immunosuppressant drugs over their lifetimes,” says Chris Larsen, MD, PhD, executive director of the Emory Transplant Center and principal investigator of the new grant. “Improvement in these transplant drugs is still a critical need for avoiding acute and late-stage rejection. Ultimately, we want to improve overall health while reducing cost through improved outcomes with fewer drugs.”

In addition to Dr. Larsen, project leaders from the Emory Transplant Center will include Allan D. Kirk, MD, PhD, scientific director of the Emory Transplant Center and a Georgia Research Alliance Eminent Scholar; Leslie Kean, MD, PhD, Emory associate professor of pediatrics and director of the Pediatric Bone Marrow Transplant Division of the Aflac Cancer and Blood Disorders Center of Children’s Healthcare of Atlanta, Stuart J. Knechtle, MD, surgical director of the liver transplant program at Emory Transplant Center and Children’s Healthcare of Atlanta, and Andrew Adams, MD, PhD, assistant professor of surgery.

“The most important feature of this award is its support for multiple investigators attacking the problems of immunosuppression from different but complementary angles,” says Kirk. “The team science approach is the best way to get results to our patients.”

Several projects funded by the new grant will aim to develop more effective transplant drugs and strategies to avoid immunosuppressant drugs altogether.

An additional project will develop strategies to overcome immune sensitization in patients who have had previous transplants, pregnancies or blood transfusions. These patients often are not candidates for transplant because of their increased risk of rejection.

For more information about the Emory Transplant Center, its research projects and clinical programs please  use the Related Resources links below.

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Help Us Honor Nurse Allison Batson and Her Gift of Life – Vote Today!

Nurse Allison Batson, Patient Clay Taber

Nurse Allison Batson with Clay Taber

Every once in awhile, you meet someone so special that they become part of you forever. For 23-year-old Emory kidney transplant patient Clay Taber, that person is Allison Batson – literally.

A few months ago, we told you the story of a transplant nurse at Emory University Hospital, Allison, and her selfless donation of one of her kidneys to Taber last January, a gift that likely saved him months on dialysis — if not his life. Allison and Clay met when he was an inpatient at Emory University Hospital fighting a rare disease called Goodpasture’s Syndrome, a life-threatening autoimmune disorder characterized by kidney disease and lung hemorrhage. Allison saw more than a patient in Clay.  She saw her own children, all close to Clay’s age.

“I learned more about Clay, his family, his life, what he saw for his future,” Allison recalls. “He wanted to get married to his sweetheart. He’d just graduated from college. The whole world was his, with the exception of this incredibly rare illness that hit him out of the blue. I have children his age, and I felt the same kind of pain his mother was feeling. Something inside me said I needed to do more.”

Though Clay’s blood type is rare, Allison was tested to be a donor and proved to be a match. On Tuesday, January 10th, Allison’s kidney was removed and transplanted into Clay’s body. Nearly half a year later, Clay has recovered well, even finding a weekend in June to marry his college love.

Though Allison has never asked for special treatment or even a hint of recognition, her colleagues recently submitted her profile to Johnson  & Johnson’s Amazing Nurses Contest. She was selected as one of 10 finalists. Voting is now up to the public. If Allison wins, she’ll receive a trip for two to Los Angeles to attend the 2012 CNN Heroes: An All-Star Tribute live broadcast show, courtesy of CNN.  Though a trip to sunny LA is quite a prize, Allison has a bigger gift in mind.

“I am once again humbled by this nomination and very excited to be recognized,” says Allison. “But more than that, my hopes for this contest are that it will spread the word about the Living Donor program.  There are more than 90,000 Americans on the waiting list for a kidney transplant. That’s 90,000 too many. Relatives, loved ones, friends and even strangers can give this lifesaving gift.”

To vote for Allison, visit http://www.amazingnurses.com. Voters can cast one vote per day until Sept. 28. The winner will be announced December 2 at the CNN Heroes: An All-Star Tribute live broadcast.

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Kidney Patients Can Now Receive Pre- and Post-Transplant Care Closer to Home

Emory Transplant CenterBeginning in May 2012, the Emory Transplant Center will provide pre- and post-transplant services for renal patients in northwest Georgia at our new location in Cartersville. Along with our two existing satellite offices in Savannah and Dublin, the new office in Cartersville means that more Georgians can receive kidney transplant evaluations and follow-up care from Emory professionals without making a trip to Atlanta.

Emory’s Kidney Transplant Program:

  • Provides comprehensive evaluations for kidney and pancreas transplantation, as well as state-of-the-art transplant follow-up care
  • Offers a highly skilled team of specialists in the care of kidney transplant patients and living donors
  • Ranks as one of the top programs of its kind in the country, with success rates higher than expected for both patient and graft survival*
  • Performed 215 kidney transplant procedures in 2011 – the largest number of transplants in a single year in the history of the program

Emory Kidney Transplant Program Satellite Locations:

Emory Transplant Center –  Cartersville
(located in the Emory Heart & Vascular Center office)
970 Joe Frank Harris Parkway, Suite 280
Cartersville, Georgia 30120

Emory Transplant Center –  Dublin
(located in the Emory Heart & Vascular Center office)
2301 Bellevue Road, Suite 1000
Dublin, Georgia 31021

Emory Transplant Center –  Savannah
(located in the St. Joseph’s/Candler Hospital)
5534 Reynolds Street, Suite 212
Savannah, GA   31405

For more information about our locations and scheduling an appointment, visit our Kidney Transplant Program website.

 

*Source: Transplant by volume, Scientific Registry of Transplants Recipients (SRTR) national database

 

A Life Free From Anti-Rejection Medication Post-Transplant?

A life free from taking anti-rejection medications post-transplant…is it possible? After transplant, patients must take multiple medications to keep their bodies from rejecting the new organ. The side effects of these immunosuppressant drugs, for many, can be grueling. Side effects range from fatigue to high blood pressure to increased risk of infection. Researchers are currently evaluating whether it’s possible for kidney transplant patients to avoid use of immunosuppressant drugs post transplant. They’ve found that it’s possible that by not only transplanting the living donor organ but also some of the donor’s immune producing cells, it  may be possible to deceive the recipient’s immune system into accepting the new organ as its own.

To evaluate the likelihood of decreased reliance on immunosuppressant drugs for kidney transplant patients, researchers collect immune system-producing stem cells and other immunity cells from the living donor’s bloodstream. They infuse transplant patients with radiation and medications to wipe out part of their own bone marrow.  This allows the donated cells to squeeze in and create a sort of ‘mixed’ immunity that prevents rejection.  In essence, a kidney transplant patient would also be receiving a bone marrow transplant.

Dr. Kenneth Newell

Dr. Kenneth Newell

At the Emory Transplant Center, researcher Dr. Kenneth Newell, is compiling a registry of kidney recipients who somehow survive despite quitting the pills on their own because they couldn’t afford them or because of side effects – a truly rare case.  Thus far, Dr. Newell has discovered about three dozen of these cases.  The research team at Emory is testing these patients for biological markers that might explain why they fared well and who else is a good candidate.  This may provide clues that a completely separate part of the immune system plays a role in organ rejection/acceptance.

In the meantime, the Food and Drug Administration (FDA) approved the drug belatacept (Nulojix®) for the prevention of graft rejection after kidney transplants.  This is the first time a new class of drugs has been developed for transplant since the 1990s.  Belatacept has the potential to improve and simplify the medication regimens of kidney transplant recipients, being a less toxic alternative to calcineurin inhibitors, with fewer side effects such as high blood pressure, high cholesterol, kidney toxicity and diabetes.  It is now being offered at the Emory Transplant Center, where Emory physicians played a role in discovering this new drug.

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“My Offer Stands.” – Emory Transplant Nurse Donates Kidney to Patient

Clay Taber, Transplant Patient with Nurse Allison BatsonEmory University Hospital transplant nurse Allison Batson has spent many years caring for patients in need of a life-saving organ transplant. She has seen many patients’ lives saved because of the gift of organ donation … and many others lost because a matching organ simply could not be located in time.

Recently though, Allison was not only in the position to provide care and comfort at the bedside of a transplant patient in desperate need of a kidney transplant, she selflessly gave of herself – literally- by becoming an organ donor to 23 year-old Clay Taber of Columbus, Georgia.

Clay graduated from Auburn University in August and is soon to marry his college sweetheart in a few months. While he has been eagerly looking toward his future, over the last few months, he’s also been battling the fight of his life.

After his graduation, Clay’s family took a celebratory beach vacation at the Gulf of Mexico – not long after the unprecedented oil spill that occurred there. A few weeks later, Clay was not feeling well.

A doctor’s visit and standard blood tests uncovered Clay had Goodpasture’s Syndrome, a rare (approximately 1-in 1 million), life-threatening autoimmune disorder related to antibody formation in the body. Goodpasture’s syndrome is characterized by renal (kidney) disease and lung hemorrhage.

There is no exact cause known for Goodpasture’s disease, a disease in which the immune system fights the body’s own normal tissues through creating antibodies that attack the lungs and kidneys. Sometimes the disorder is triggered by a viral infection, or by the inhalation of gasoline or other hydrocarbon solvents – such as those found in crude oil.

Nurse Allison Batson, Patient Clay Taber

Nurse Allison Batson with Clay Taber

While Clay was lucky that the disorder was discovered before his lungs were affected, he was now suffering from complete kidney failure. He was transferred to Emory University Hospital in Atlanta, where he would spend numerous weeks on the 7th floor – the transplant unit, where he would undergo weeks of dialysis and plasmapheresis (blood purification procedure used to treat several autoimmune diseases.)

And that’s where the bond began.

“Immediately when Clay came onto our unit, he became a special patient that everyone just gravitated to,” said Allison Batson. “Here was this young man with everything in his life ahead of him, and he was fighting for his life. He quickly became friends of many of the staff, and really was just a tremendous inspiration to us all.”

Allison continued to visit with Clay during his weeks at the hospital, and a deeper connection began to form than the typical nurse-patient bond.

“I learned more about Clay, his family, his life, what he saw for his future. He wanted to get married to his sweetheart. He just graduated from college. The whole world was his, with the exception of this incredibly rare illness that hit him out of the blue. I have children his age, and I felt the same kind of pain his mother was feeling. Something inside me said I needed to do more.”

Soon Clay was strong enough to return home, where he would continue to receive dialysis treatment for a few months while waiting for a donor organ. Because Clay’s blood type is O-negative, finding a matching donor would prove to be challenging.

Clay’s mother, Sandra, would be tested as a possible match. She, however, would not qualify to be Clay’s organ donor. Then in late October, during a visit to Emory and the transplant unit where he regularly visited with friends and well-wishers, Clay, of course, also met with Allison.

“She said ‘If you’ll let me do this, I want to donate my kidney to you,” Clay recalls. “Something at that point just hit me. There are so many people in need of an organ transplant and have been waiting like me – even longer than me in many cases. And here is Allison offering to do this amazing thing. When she said ‘If you’ll let me,’ there was just something in those words. I couldn’t say no.”

Soon after, Allison would undergo the donor testing process that would eventually confirm her as a perfect match for Clay.

“People have asked me why I would do this for a stranger, or what if I had a family member in need one day, or why would I risk my own life or health for someone I barely know. My answer is because I can. Sure, I have children who might possibly be in need one day, but here was this young man right in front of me who needs help – today, and I am in a position to help him – today. If what I do for Clay causes more awareness among others that live organ donation is a possibility, then I can only hope that other lives will be saved because of my actions.”

On Tuesday, January 10th, the families of both Allison and Clay gathered in the early morning hours at Emory University Hospital. Smiles, tears and hugs were abundant between people who had formed an unbreakable bond over the course of the last few months, and had, in effect become extended family to one another.

In Operating Room #9, Allison underwent surgery to remove her kidney, while Clay was prepped for surgery just 30-feet away in Operating Room #8. Hours later, both patients were resting comfortably on the 7th floor of Emory University Hospital, where they had met by chance just months before. Both ready to start the new year in incredible fashion – with a new lease on life for Clay, and as a hero for Allison.

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