New Mammography Guidelines

mammogramAlthough the American Cancer Society (ACS) confirms that mammography saves lives, the organization issued new breast cancer screening guidelines on Oct. 20 that recommend women at average risk for breast cancer start getting annual mammograms at age 45. The previous recommendation was to start at age 40, and I will continue to recommend that women get yearly screening mammograms starting at age 40.

Evidence shows that the most lives are saved when screening starts at age 40. Although breast cancer is a little less common in women aged 40 to 44, this group receives the same life-saving benefit from screening mammography that older women do. As a radiologist specializing in breast cancer detection and diagnosis, I see this first-hand. My colleagues in the American College of Radiology agree and are also continuing to recommend that yearly screenings begin at age 40.

The new ACS guidelines note that the “harms” associated with screening may outweigh the benefits in women age 40-44. It is vital that women compare the magnitude and implication of the harms versus benefits associated with screening mammography. The harms they identify are about getting false positive readings from mammograms that can result in women being called back in for more imaging or an ultrasound. About 10% of women are recalled for these additional tests and the vast majority are cleared at that point. About 1 – 2% of patients who are recalled receive a needle biopsy using local anesthetic.

The benefits include saving lives and finding cancers smaller and earlier so that less aggressive treatment is required. I believe most women will agree that the drawbacks pale in comparison to the benefits of screening, and will choose to proceed with yearly screening. In fact, the ACS declares that yearly screening is beneficial and something that the majority of women would want, as long as they are healthy and have a 10 year or longer life expectancy. It is vital that we preserve a woman’s access to this life-saving technology so that she may choose to screen.


About Dr. Newell

Newell_MaryMary S. Newell, MD, began practicing with Emory Healthcare in 2001 where she is a board certified radiologist specializing in breast cancer imaging and diagnosis. Dr. Newell has interests in emerging imaging technologies, teaching, and healthcare policy.

Dr. Newell chairs the American Board of Radiology Maintenance of Certification (MOC) Breast Committee and the American College of Radiology Joint Practice Guidelines and Technical Standards and Appropriateness Committee on Criteria. She is Head of Curriculum Assessment for the Society of Breast Imaging and Special Consulting Editor for CME for the American Journal of Roentgenology. She also serves as the treasurer for the Georgia Radiologicial Society, is a councilor to the American college of radiology representing the state of Georgia, and serves on numerous committees institutionally and nationally.

Dr. Newell earned her medical degree from the University of Michigan Medical School. She then completed her residency in diagnostic radiology and fellowship in body imaging at the St. Francis Hospital in Illinois. Dr. Newell’s research focuses on discovery and evaluation of new imaging modalities for future use in breast cancer screening and detection.

Pancreatic Cancer: Incidence and Outlook

Pancreatic cancer increases with age and most people are between 60 to 80 years old when diagnosed. Early pancreatic cancer often does not cause symptoms. Pancreatic cancer can affect anyone. People with a family history of pancreatic cancer in first degree relatives have an increased risk.

Pancreatic cancer specialist, Dr. David Kooby from Winship Cancer Institute of Emory University talks about why the disease is so prevalent and why it is so difficult to treat.

Learn more about Winship Cancer Institute of Emory University.

Winship Cancer Institute Expands Hospital Access

winship expands sign picWinship Cancer Institute has expanded access to its high quality cancer care in alignment with its broad clinical research program at both Emory Saint Joseph’s Hospital (ESJH) and Emory Johns Creek Hospital (EJCH). In addition, Winship has established the Winship Cancer Network as a means to improve access to such vital services throughout Georgia and the Southeast.

Longstanding and continued support from the Robert W. Woodruff Foundation has enabled Winship to advance cancer care and access to services like these for tens of thousands of patients throughout Georgia and beyond.

In addition to expanding services at ESJH and EJCH, the Woodruff Foundation’s most recent grant will be used to expand and improve Winship’s Shared Resource portfolio with special emphasis on its Cancer Prevention and Control Research Program. Researchers in this program are continually evaluating the best methods to reduce and eliminate the development of cancer among high-risk individuals across Georgia and the Southeast.

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Emory Saint Joseph’s Hospital

Recurrent Prostate Cancer: Where is it?

Tiffany Dunphy and Van Jackson, radiation therapists at Winship at Emory Saint Joseph's Hospital, work with prostate cancer patients undergoing radiation treatment.

Tiffany Dunphy and Van Jackson, radiation therapists at Winship at Emory Saint Joseph’s Hospital, work with prostate cancer patients undergoing radiation treatment.

“It’s a lot easier to plan the attack, if we know where the enemy is,” says Winship urologist Peter Nieh, MD. “If a cancer is still localized, we may want to try salvage therapy, either radiation or surgery, before advancing to something systemic.”

Depending on how primary treatment took place, a prostate cancer often comes back in the prostate bed (where the prostate gland was), and may appear in nearby lymph nodes. In advanced cases, the cancer may spread to the bones.

Emory radiologist and Winship member David Schuster, MD and radiochemist and Winship member Mark Goodman, PhD have been developing a PET (positron emission tomography) imaging probe that shows considerable potential for detecting recurrent prostate cancer.

Usually in PET imaging, radioactive glucose is injected into the body, and since cancer cells have a sweet tooth, they take up a lot of the radioactive tracer. But the tracer also appears in the urine, complicating prostate cancer detection efforts since the prostate is so close to the bladder. In contrast, the probe 18F-FACBC, based on amino acids, is taken up by prostate cancer cells but doesn’t appear as much in urine.

FACBC has its limitations. It also may be taken up in benign prostate hyperplasia or inflammation. This means it probably won’t be as useful by itself for evaluating primary prostate cancers, but it has a lengthening track record in recurrent cancer.

In a 2011 publication, Schuster and his colleagues compared FACBC to ProstaScint, a commercially available probe. FACBC showed superior sensitivity and specificity in detecting tumors outside the prostate bed. Schuster is now collaborating with Winship radiation oncologist Ashesh Jani, MD to study FACBC’s benefits in designing radiation treatments for patients with recurrent prostate cancer after prostatectomy.

In Jani’s clinical trial study for recurrent prostate cancer, which lasts until 2017, one group of patients is examined using FACBC, while another gets conventional imaging. The question is whether using information gleaned from FACBC to direct the radiation results in a longer lasting remission than with the control group.

Marble countertop salesman Paul Reckamp, who was a participant in Jani’s study, keeps a file on his phone noting his PSA levels for the last several years. Reckamp had a radical prostatectomy in July 2010 at Emory Saint Joseph’s Hospital, but the cancer appeared to come back a year and a half later. FACBC imaging confirmed that the cancer had appeared in nearby lymph nodes but not elsewhere, and doctors could then plan radiation treatment that drove his PSA levels back down again.

“I couldn’t have been more pleased with the study,” he says. “It told me and the doctors what we wanted to know.”

As a National Cancer Institute (NCI) designated cancer center, Winship Cancer Institute of Emory University’s participation in clinical trials ensures our prostate patients have access to progressive resources and technology. For men with recurrent prostate cancer, there are newer methods of imaging such as magnetic resonance imaging (MRI) and positron emission tomography (PET). 

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Scientists of the Next Generation

As children we have all been to the doctor, visited the dentist, perhaps even sat in the cockpit of a plane. Anyone ever sit in front of a cryo-electron microscope, play with the dials on a mass spectrometer, or manipulate the genetic code? Most of us probably did not have that opportunity. I surely did not. So how will children, that is, our next generation of scientists, even consider being a scientist without ever knowing what a scientist does?

I am a cancer biologist with a lab focused on cancer metastasis (spread of the cancer). We study how cancer metastasis occurs in subtypes of patients to develop new treatments designed for these particular patients. On the side, I have also traveled throughout Georgia visiting over 3,000 students in K-12th grade to teach them about science and scientists. I have had the fortunate experience of visiting over 40 schools ranging from urban to rural, and public to private. I can state with 100% certainty that children are extremely interested in real science. Whether it has been high school assemblies or elementary school STEM fairs, students (adults too) are excited, enthusiastic, and most of all curious. They are curious not just about science itself, but what a scientist is and what a scientist does.

This signals to me that we need to make science more accessible. City wide science fairs, STEM fairs in school, career days, Twitter chats (#scistuchat), and experiential science in the classroom are excellent approaches. But scientists too need to open up their labs to reach out as well. We, as a professional group, need to show that we are not a bunch of mad scientists in the lab running through billows of smoking Erlenmeyer flasks trying to cure cancer. Instead we are well-coordinated teams of researchers and clinicians, working in fields that include math, engineering, informatics, surgery, and genetics that share a common goal of helping humans.

So, to all scientists out there, I propose to just take out your phone and record a 1-minute, impromptu lab tour, and send it to social media (#labtour). This gives anyone access through the locked lab doors to see what we do and who we are. My lab’s really quick video is posted here and embedded below.

The next generation of scientists are sitting out there right now learning in our classrooms. Within their minds are new treatments for cancer, novel screening approaches for neurodegenerative diseases, ideas for space exploration, and new robotic technologies. It is up to teachers, scientists, families, and communities to engage these students, make science more accessible, and let them know what is out there. I believe that if they can know the names and abilities of every single super-hero, princess, and cartoon character by age 7, they can surely know the parts of a cell. Let’s challenge them and see what we get!

About Dr. Marcus

Adam Marcus, PhDAdam Marcus received his PhD in cell biology from Penn State University in 2002 and went on to do a post-doctoral fellowship in cancer pharmacology at Emory University. Dr. Marcus is an Associate Professor at Emory University School of Medicine and has developed his own laboratory which focuses on cell biology and pharmacology in lung and breast cancer. Dr. Marcus’ laboratory studies how cancer cells invade and metastasize using a combination of molecular and imaging-based approaches. For more information about Dr. Marcus and his outreach and research efforts, please use the related resources links below. You can also follow Dr. Marcus on Twitter @NotMadScientist.

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It’s Melanoma Awareness Monday: Reduce Your Risk

melanoma awarenessDid you know that melanoma cases in the United States are growing faster than any other cancer? Malignant melanoma is a type of skin cancer that can be deadly if it spreads throughout the body. It usually grows near the surface of the skin and then begins to grow deeper, increasing the risk of spread to other organs. Detecting and removing a malignant melanoma early can result in a complete cure. Removal after the tumor has spread may not be effective.

Melanoma can occur anywhere on the skin, including areas that are difficult for self-examination. Many melanomas are first noticed by other family members.

Most patients with early melanoma have no skin discomfort whatsoever. See a doctor when a mole suddenly appears or changes. Itching, burning or pain in a pigmented lesion should cause suspicion, Visual examination remains the most reliable method for identifying a malignant melanoma.

Avoiding exposure to ultraviolet radiation is the best way to prevent melanoma and other skin cancers. Melanoma Monday is May 4th so here are a few tips for reducing your risk:

  • Avoid direct exposure between 10am and 4pm, opt for shade
  • Cover up with clothing (broad brimmed hat, sunglasses, long sleeves, etc.)
  • Use a sunscreen of SPF 30 or higher every day (including lip balm with SPF 30)
  • Apply 1 ounce (2 tablespoons) of sunscreen to the entire body, 30 minutes prior to going outdoors; reapply every 2 hours or after excessive sweating or swimming
  • Keep newborns out of the sun; if it cannot be avoided use a sunscreen with physical blockers to exposed areas (see below)
  • Avoid tanning beds
  • Remember water, sand, and snow reflect the sun; and clouds allow 70-80% UV penetration

Have fun this summer, but remember these tips for sun safety.

About Dr. Chen

chen, suephySuephy Chen, MD, MS, began practicing at Emory Healthcare in 2000 and has been board certified in dermatology since 1997. In addition to melanoma, Dr. Chen has clinical interests in pruritus, psoriasis, and atopic dermatitis.
Dr. Chen is a member of the Cancer Prevention and Control Research Program at Winship Cancer Institute of Emory University. She is also a member of the American Academy of Dermatology, the Society for Investigative Dermatology, and the Women’s Dermatology Society. In addition, she is a founding member of the Pigmented Lesion Group of the Melanoma Prevention Working Group.

Dr. Chen earned her Doctor of Medicine from Johns Hopkins University School of Medicine. She completed her internship at the Beth Israel Hospital, a Harvard University teaching hospital, before continuing on to a dermatology residency at Emory University Hospital. She obtained her Master of Science in Health Services Research at Stanford University and completed her fellowship at Stanford Hospital.

Dr. Chen is interested in quantifying the burden of skin disease, particularly the quality of life and economic burden on both patients and society as a whole. She is also interested in testing new technologies in the delivery of dermatologic care. She has contributed to numerous phase I-IV clinical studies of novel therapeutic regimens for the treatment of both inflammatory skin disorders and skin cancers.

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Dermatologist #1 Skin Care Rule – Wear Sunscreen!
Top 5 Skin Protection & Skin Cancer Prevention Tips for UV Safety
Skin Cancer Chat

Kidney-Saving Robotics & Education

Saving kidneys from cancerous tumors and stones using minimally invasive techniques is my specialty. I’ve performed nearly 200 kidney operations in the last year alone and I recently launched a robotic kidney tumor program for Winship Cancer Institute at Emory Saint Joseph’s Hospital. Kidneys are essential to life but most people aren’t aware of their extraordinary function until there’s a problem. As a vital organ, kidneys are a filter for the body and they make urine to rid the body of waste toxins.

How would you know if you have a possible kidney concern? Check for a change when going to the bathroom. Kidney cancers in the early stages usually do not cause any signs or symptoms, but patients will sometimes experience signs that should be brought to a doctor’s attention, such as:

  • Noticing blood or very dark urine
  • Flank/back pain on one side (not caused by injury)
  • A mass (lump) on the side or lower back
  • Fatigue (tiredness)
  • Loss of appetite
  • Weight loss not caused by dieting
  • Fever that is not caused by an infection and doesn’t go away

Contact your doctor if you see changes like these. Recognizing your body’s warning signals can reduce your risk of serious disease, but the best option of all is prevention.

Kidney cancer prevention starts with smoking cessation and being aware of any history of kidney cancer in your family. The National Cancer Institute also identifies obesity as a known risk factor for kidney cancer, so take steps to manage your weight, exercise as a doctor prescribes for your individual condition, and eat whole foods that are rich in nutrients. Everyone should get regular check-ups.

When tumors or stones do develop, my job is to preserve this vital organ by using a minimally invasive procedure such as laparoscopic or robotic surgery (see video below). Not every tumor in the kidney is cancerous so options other than removing the entire kidney should be evaluated. Emory surgeons have been pioneers in using technologies like these to do organ-sparing cancer surgeries and complex stone surgeries.

As a specialist, I typically see patients after they are found to have a tumor or mass in the kidney or start experiencing symptoms. Let’s make prevention a part of your routine.

See Dr. Pattaras discuss this special type of organ-sparing robotic surgery:

About Dr. Pattaras

pattarasJohn G. Pattaras, MD, FACS, is an Associate Professor of Urology at the Emory University School of Medicine, Chief of Emory Urology services at Saint Joseph’s Hospital and Director of Minimally Invasive Surgery.

As the Director of Minimally Invasive Surgery, Dr. Pattaras started laparoscopic and robotic urologic surgery program at Emory University. Over the past 14 years, the program has expanded to become the premier laparoscopic and robotics program in Atlanta serving patients from Georgia, neighboring states as well as international patients. The program offers highly specialized minimally invasive surgery that includes organ-sparing cancer surgery and complex stone surgery. Patients attending Emory Urology for cancer treatment have the unique opportunity to be cured of their disease while at the same time preserve their vital organs, their functionality and quality of life.

Dr. Pattaras is a diplomate of the American Board of Urology (2002) a Fellow of the American College of Surgery.

In addition to his dedication to Emory patients, Dr. Pattaras is also involved in humanitarianism outside Emory. On an annual basis, he volunteers his time to organize and head a team of Emory medical students to Haiti. The team provides free urologic care including surgical treatment to indigent Haitian patients with urologic conditions.

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5 Early-Distress Warnings of Digestive Cancer

pancreatic cancer live chatWhen you think of digestion you probably don’t think about the pancreas, but it sits right behind the stomach and works to provide essential digestive functions. The pancreas, only about 4- 6 inches long, is widely known for producing insulin, an important hormone that regulates blood sugar levels, but it also assists the body in the absorption of nutrients into the small intestine.

Pancreatic cancer increases with age and most people are between 60 to 80 years old when diagnosed. Early pancreatic cancer often does not cause symptoms, however there are five early warning signs that we can all be aware of to better advocate for our health.

  1. Yellow eyes or skin.  The pancreas uses a greenish-brown fluid made in the gallbladder, called bile, to help the small intestine in digestion. If a tumor starts in the head of the pancreas, it can block or press on the bile duct and cause bile to build up. This back-up causes yellow discoloration, called jaundice.
  2. Belly pain.  Pain has been described as distressing, as compared to a sharp cramp or ache. Pain may go away when you lean forward because it and spreads toward the back.
  3. Change in stool.  Pale, floating, smelly stools. Or dark stools. Let your stool be a guide. If a pancreatic tumor prevents digestive fluids from reaching the intestine, the result is an inability to digest fatty foods. Anytime there is a change with digestion then check in with your doctor. It may not be a sign of digestive cancer, but you do need to be aware of your own body function to determine what is or is not “normal.”
  4. Lack of appetite.  Or sudden, unexplained weight loss. A drop in appetite and a tendency to feel full after eating very little is something to be aware of. Again, it may not be alarming but you do need to be aware of your own body function to determine what is or is not “normal.”
  5. Diabetes, especially if unexpected from regular check-ups.  Most diabetes diagnoses are not due to pancreatic cancer; however, research studies show that pancreatic cancer patients have a higher rate of diabetes diagnosis than the general populace. Knowing your family history of pancreatic cancer and having a baseline of regular screening will help your doctor evaluate if additional tests should be done.

Being an advocate for your health starts with healthy behaviors; tobacco use, particularly cigarette smoking, accounts for 20-30% of pancreatic cancer. Knowing risk factors you should avoid (such as smoking) and being aware of what your body is signaling will help you in early detection as well as potential outcome.

Management of cancer requires a multidisciplinary team of healthcare specialists. Winship’s pancreas cancer team includes surgeons, medical oncologists, radiation oncologists, gastroenterologists, pathologists as well as pain specialists, nutritionists and social workers. For patients with early stage pancreatic cancer, the Whipple surgical procedure is the best option for long-term survival. Winship Cancer Institute of Emory University surgeons perform a large number of Whipple procedures every year; a high volume of these procedures directly translates into the expertise needed to perform the procedure safely. According to published data, mortality rates from Whipple surgery are four times lower at hospitals performing a high volume of the procedure, such as Emory. Some patients may be candidates for laparoscopic or robotic surgery, which may improve both recovery and cosmetic appearance after surgery. Winship at Emory surgeons are leading the world in this area as well. If diagnosed with cancer it’s important to get to Winship, first.

Continue learning about pancreatic with a conversation; all are welcome to attend an online open-forum discussion about pancreatic cancer. We will answer your questions about pancreatic cancer risk factors, symptoms and therapy on Tuesday, May 12th, 2015 at noon.

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About Dr. El-Rayes

Dr. El-Rayes, Colon Cancer SpecialistBassel El-Raye, MD, is the Director of the GI Oncology Clinical and Translational Research Program, Associate Cancer Research Director for Clinical Research at Winship Cancer Institute of Emory University and Professor of Hematology and Oncology at Emory University School of Medicine. Dr. El-Rayes earned his bachelor’s degree in biology and doctoral degree from the American University of Beirut. He then completed his residency in internal medicine and fellowship in hematology and medical oncology at Wayne State University, Detroit. He was on faculty at Wayne State University Karmanos Cancer Institute from 2003-2009. Dr. El-Rayes clinical interests include gastrointestinal malignancies specifically pancreatobiliary and neuroendocrine cancers. He is principle investigator on multiple investigator initiated trials. He has served on the gastrointestinal committee for Southwest Oncology Group (SWOG) and Radiation Oncology Cooperative Group (RTOG). He currently serves on the National Cancer Institute Neuroendocrine Tumor (NET) Task Force. He also serves as Co-chair of Hoosier Oncology Group (HOG) Cancer Research Network – Gastrointestinal Clinical Trials Working Group. Dr. El-Rayes is a Georgia Cancer Coalition Distinguished Clinical Scholar. He has published over 90 peer reviewed articles in elite journals including Journal of Clinical Oncology and Cancer Research.

About Dr. Kooby

David Kooby, MDDavid A. Kooby, MD, FACS, specializes in laparoscopic/robotic and open surgical treatment of liver, bile duct, pancreas, stomach, and colon tumors/cancers. He also has expertise with tumors and diseases of the spleen, adrenal glands, and retroperitoneum. He has taught many national courses on laparoscopic resection of the liver, pancreas, and colon, and is frequently invited to speak at national conferences. He received his MD at the State University of New York, Downstate Medical College, Brooklyn, NY, in 1994; completed his surgical residency at Vanderbilt University, where he won medical student and resident teaching awards. He completed both bench research and clinical fellowships at Memorial Sloan-Kettering Cancer Center, New York, NY. He was recruited by Emory in 2003, and is currently an Associate Professor of Surgery in the Division of Surgical Oncology, Director of Surgical Oncology at Emory/Saint Joseph’s Hospital, and Director of Minimally Invasive GI Surgical Oncology. He serves on several national committees including the task force charged with updating the staging of hepatobiliary malignancies for the American Joint Committee on Cancer’s Cancer Staging Manual, the research and education committee for the American Hepato-Pancreato-Biliary Association, and the Hepatobiliary Working Group for the Society of Surgical Oncology. He is leader in multicenter clinical research and is a national leader in minimally invasive pancreatic surgery.

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Steve Jobs, Pancreatic Cancer & the Whipple Procedure

Screenings Help Catch Head and Neck Cancers

head and  neck cancer screeningsA recent study reported in JAMA Otolaryngology found that most Americans know little to nothing about head and neck cancers and could not name the most common symptoms and risk factors. This is a problem. If you wait months or even years to get a sore in your mouth or swelling in your neck checked by a doctor, you could be ignoring a sign of head and neck cancer that’s progressing. And, as with many other forms of cancer, the earlier a head and neck or oral cancer is diagnosed, the less invasive the treatment is and the higher the chance of cure. As a doctor who sees many patients with these cancers, one message comes through loud and clear: don’t ignore symptoms.

On April 17th, doctors and staff with Emory’s Department of Otolaryngology and Head and Neck Surgery will hold a free head and neck screening at Emory University Hospital Midtown (EUHM). This is a chance for patients who might be suffering any symptoms or have any of the stated risk factors for head and neck cancer, to have a simple, free exam. This involves a physical exam of the neck and inside the mouth, including the middle throat, soft palate, the base of the tongue, and the tonsils. As a best practice, Emory Healthcare suggests this screening procedure should also be a part of a routine dental visit.

Get a Free Head and Neck Screening on April 17th:

Emory University Hospital Midtown
Department of Otolaryngology and Head and Neck Surgery
9th Floor, suite 4400
550 Peachtree Street, NE
Atlanta, GA 30308

Date: 4/17/2015
Time: 8:00 AM- 12:00 PM

This is a first come – first serve walk in clinic. No Appointment Necessary.

For more information:
Phone: (404) 778-3381

Important Information on Head and Neck Cancers:

Head and neck cancer involves skin or mucosal surfaces of the head and neck and includes cancers of the mouth, throat, nasal sinuses, skin of the head and neck and cancers of the major salivary glands. Head and neck cancers account for approximately 3% of cancers diagnosed every year in the United States and affect more than twice as many men as women.

Symptoms of head and neck cancer vary somewhat by site but often include non-healing ulcers in the mouth, unexplained loosening of the teeth, and pain that does not improve. Patients with cancers of the throat or salivary glands will often come in with a painless lump in the neck that does not resolve with antibiotics. Other patient will have ear pain or difficulty and/or pain when swallowing.

Potential Risk Factors for Head and Neck Cancer:

Head and neck cancer has historically been most associated with tobacco and alcohol abuse, and may also be associated with marijuana use. Recently, the human papilloma virus (HPV), a virus commonly passed during sexual activity, has been widely implicated in cancers of the tonsils and base of tongue. According to the Centers for Disease Control and Prevention, HPV usually goes away by itself and does not cause health problems, but may be responsible for a growing number of oral cancers. Other risk factors include poor oral hygiene, radiation exposure, and Epstein-Barr Virus (Mononucleosis).

Every year, the Head and Neck Cancer Alliance promotes an awareness week in April that is highlighted by free head and neck cancer screenings all across the country. Our own free screening at EUHM is open to anyone in the community and we enthusiastically invite you to participate. We look forward to providing you with the opportunity to proactively advance your health on April 17!

About Dr. El-Deiry

Mark El-Deiry, MDMark W. El-Deiry, MD, is an Assistant Professor in the Department of Otolaryngology – Head & Neck Surgery, in the Emory University School of Medicine. He also serves as Chief of the Division of Head and Neck Surgery, Department of Otolaryngology, and Director of the Head and Neck Oncology Surgery Center. He is a member of the surgical team that specializes in treating patients with head and neck cancers including complex microvascular reconstructive surgery.

El-Deiry and the entire head and neck team are interested in promoting screenings that help detect head and neck cancers in early stages. His research interests include quality of life in head and neck cancer survivors and quality outcomes involved with treating patients with advanced stage head and neck cancer.

Related Resources

Takeaways from Dr. Saba’s Head and Neck Cancer Chat

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HPV and Head and Neck Cancer Chat

Taking a Stand in Favor of E-Cigarette Regulation

e-cigarette regulationIt has taken us over 50 years of careful regulation with tremendous pushback to strip the tobacco companies of their ability to aggressively and falsely market cigarettes as safe products. The advent and popularity of e-cigarettes could wipe out much of that progress and endanger an entire generation of young people who are attracted to the slickly packaged cartridges, marketed to a youthful generation as a safe alternative to tobacco burning cigarettes.

I firmly believe that the United States Food and Drug Administration should have full authority to regulate e-cigarettes; the same full authority the agency currently has to regulate regular tobacco products. E-cigarettes are not made up of benign compounds. In fact, some of the ingredients such as formaldehyde are known carcinogens. With recent introductions of e-cigarettes from big tobacco companies such as Philip Morris, I believe they will pose some of the same risks as tobacco-burning projects unless they are regulated.

We know that nicotine is highly addictive, whether it is delivered from an e-cigarette, a regular cigarette or a patch. There is some data that nicotine may promote certain cancer signaling networks. There is also some very good evidence in young people that nicotine can cause the rewiring of the brain circuitry. Of greatest concern is recent data obtained from careful studies conducted by the Centers for Disease Control (CDC) that show that people who use e-cigarettes are twice as likely to consider smoking tobacco burning products. In my view, this makes e-cigarettes a Trojan Horse that allows tobacco products into the lives of young people without the proper FDA regulation.

The full range of health risks posed by e-cigarettes is unclear because they have not been fully studied. Just because we don’t have all the scientific evidence does not mean that e-cigarettes should get a free or easy ride. They should be held to the full high bar, especially because we don’t currently understand all of the dangers they pose.

My biggest concern about e-cigarettes is that they are easily marketed to teens and young adults. The campaigns seem to be working since e-cigarette use has almost tripled in the last three years. Only 19% of Americans are active cigarette smokers, but that’s still far too high in my book. We should be concerned as a society that smoking rates will increase as a result if e-cigarettes continue to be sold without any regulation. E-cigarettes are a step backward in our goals to move towards a tobacco free society.

About Dr. Khuri

Fadlo Khuri, MDFadlo R. Khuri, MD, deputy director of the Winship Cancer Institute of Emory University and Professor and Chairman of the Department of Hematology & Medical Oncology, Emory University School of Medicine, and executive associate dean for research of Emory University, is a leading researcher and physician in the treatment of lung and head and neck cancers. He is Editor-in-Chief of the American Cancer Society’s peer-reviewed journal, Cancer.

Dr. Khuri’s contributions have been recognized by a number of national awards, including the prestigious 2013 Richard and Hinda Rosenthal Memorial Award, given to an outstanding cancer researcher by the American Association for Cancer Research.

An accomplished molecular oncologist and translational thought leader, Dr. Khuri has conducted seminal research on oncolytic viral therapy, developed molecular-targeted therapeutic approaches for lung and head and neck tumors combining signal transduction inhibitors with chemotherapy, and has led major chemoprevention efforts in lung and head and neck cancers. Dr. Khuri’s clinical interests include thoracic and head and neck oncology. His research interests include development of molecular, prognostic, therapeutic, and chemopreventive approaches to improve the standard of care for patients with tobacco related cancers. His laboratory is investigating the mechanism of action of signal transduction inhibitors in lung and aerodigestive track cancers.

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